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The targeting construct inserted IRES, tdTomato, T2A self-cleaving peptide, iCre recombinase, and an FRT site-flanked PGK-NEO-BGHpA cassette downstream of the stop codon of the Fcgr1 gene by CRISPRCas9-mediated homologous recombination in mouse ES cells. Mice harboring the targeted allele were subsequently crossed with Rosa26FLPe mice to remove the NEO cassette. (J:338195)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
