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A targeting vector was constructed such that a Foxp3 cDNA lacking exons 2 and 7 was inserted at the translation initiation ATG codon of Foxp3 and the TGA stop of Foxp3 was replaced by a 2A peptide-GFP cassette followed by a double polyadenylation signal (pA) and an FRT-flanked neomycin cassette. The neomycin cassette was removed via flp-mediated recombination. (J:338777)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
