CRISPR/Cas9 technology inserted loxP sites in introns flanking exon 2, which contains triplets encoding the catalytic center of the protein (D144N and D146N). (J:337629)
Basic Information
(C57BL/6JTar x CBA/WTar)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count