CRISPR/cas9-mediated recombination using 2 guide RNAs created a deletion of exon 3. Immunoblot analysis confirmed the loss of expression in testes from homozygous mice. (J:336774)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count