A CreERT2 with an FRT-flanked neomycin cassette replaced the translation START codon (ATG) in exon 2 of the Gnat2 gene by homologous recombination in the ES cells. Male chimeras were bred to ACTB-FLPe females for germline transmission and neomycin cassette removal. (J:338407)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count