The cDNA of iCre recombinase gene under the control of the mouse Acrv1 promoter sequence and hygromycin-resistant cassette, flanked by flippase recognition target sites, was inserted into the Gt(ROSA)26Sor locus. After germline transmission, the mice were crossed with the Flp-deleter line to eliminate the hygromycin cassette. (J:338406)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count