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Using recombination-mediated genetic engineering, a loxP-EM7-Neo-loxP ligated to Mafb 5' segment and an FRT-Neo-FRT-loxP ligated to Mafb 3' segments were introduced into mouse embryonic stem cells. Successfully recombined clones were injected into blastocysts to make loxP-flanked Mafb-Neo mice and crossed to the FLP-expressing line to remove the Pgk-Neo cassette. (J:338559)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
