CRISPR/cas9 genome editing is used to insert an in-frame T2A ribosome skipping sequence and Cre recombinase/ERT2 fusion immediately following the final M366 residue in exon 7. The inserted sequence is not expected to affect expression of Dcx. (J:343514)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count