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An AGC to GAC change resulting in a serine to aspartate substitution at amino acid 82 (p.S82D) was introduced in exon 2. A loxP-flanked neomycin selection cassette was inserted upstream of exon 2 and removed via cre-mediated recombination. This change results in a phospho-mimetic mutation mimicking constitutive CDK1 phosphorylation. (J:338489)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
