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The transgenic construct contains the mouse Foxf1 gene (bacterial artificial chromosome clone, RP23-55G4) modified by BAC recombineering methods to insert the tdTomato coding sequence, a polyA sequence, an FRT-flanked PGK neo:gb2:kanamycin inserted into exon 1 of the Foxf1 gene. Transient flp infection removed the neo and kanamycin cassette. The final engineered BAC used for transgenic mouse production contained approximately 116,000 base pairs of DNA upstream from the tdTomato start site. The construct is followed by a chloramphenicol selection marker. The BAC clone does not include any other known genes. (J:338371)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
