A floxed neo-P2A-Cre cassette was inserted into the 3' UTR in the last exon 4 of the Oprk1 gene via homologous recombination in the ES cells. The neo-selection cassette was subsequently removed. (J:338351)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count