A modified BAC construct was generated that consisted of an insertion immediately upstream of the stop codon in exon 3 of the Ccl2 gene of nucleotides encoding the HA peptide (-YPYDVPDYA-), followed by a 19 residue aphthovirus 2A cleavage site (-APVKQTLNFDLLKLAGDVESNPGP-), a furin cleavage site (-RAKR-), and aa 2239 of enhanced GFP. The EGFP coding sequence was followed by a stop codon. (J:171379)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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Insertion
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--
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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