The transgene contains the CAG promoter driving expression of the mouse gene with the mutation resulting in the amino acid substitution of aspartic acid with alanine at position 400 (D400A). Lines 1 and 2 were generated. (J:104881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count