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Using CRISPR/Cas9 technology, a 1.5kb fragment containing the codon-optimized FLP recombinase (FlpO) and a bovine poly(A) sequence was inserted between the 5 UTR and 1st exon of the Prox2 gene by homology-directed repair. (J:337785)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
