A floxed neomycin resistance cassette, IRES sequence and mCitrine (YFP) reporter gene were inserted into the 3' UTR. Homology arms flanking the 5' and 3' ends of the 1.9 kb enhancer (Enh) sequence was replaced with the deltaEnh-hygro cassette to delete the enhancer in one allele via homologous recombination in the ES cells containing Bcl11btm1.1Evrline described in J:260615 and Bcl11btm1Hykuline described in J:290296. (J:290296)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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