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A nuclear tdTomato reporter was inserted immediately upstream of the coding region in exon 3 of the gene. The reporter is followed by an A2 self-cleavable peptide, allowing independent production of the tdTomato and the IL-18BP proteins. An frt-flanked neomycin selection cassette was inserted into intron 7, then subsequently removed after selection via FLP-mediated recombination in the germline. (J:337716)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
