Rorb^hstp-5J

This spontaneous thymine to cytosine point substitution in the ATG start codon of exon 1a has exon 3 as the next in-frame start codon so is predicted to cause a start-loss variant disrupting the first zinc finger domain. Expression of the Rorb1 transcript in brain and retina is significantly increased and the Rorb2 transcript significantly decreased in retina. (J:337403)