CRISPR/cas9 genome editing is used to delete the entire coding region. sgRNA-1 (TGACCCGCCGTAAGGGCCTG) and sgRNA-2 (AGGCTCCGAGGCGCCGACGT) targeted upstream of exon 1 and downstreamof exon 7. (J:337553)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
Intragenic deletion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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