CRISPR/cas9 genome editing is used to delete the entire coding region. sgRNA-1 (TGACCCGCCGTAAGGGCCTG) and sgRNA-2 (AGGCTCCGAGGCGCCGACGT) targeted upstream of exon 1 and downstreamof exon 7. (J:337553)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count