CRISPR/Cas9 genome editing technology was used to insert loxP sites flanking exon 2. qPCR confirmed the depletion of Dis3l2 transcripts in growing and fully grown germinal vesicle (GV) oocytes. (J:337555)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count