CRISPR/Cas9 genome editing technology using two sgRNAs which target the second and the twelfth exons, respectively, was employed to generate a 47612 bp deletion of the entire coding region. No protein band was immunodetected in homozygous null testes. (J:337548)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count