Two forward loxP sites were inserted flanking exons 2 and 3, along with a downstream frt-flanked neomycin selection cassette. The frt-flanked neomycin selection cassette was removed in the germline via FLP-mediated recombination. (J:247755)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count