Stmn2^em1Jmi

CRISPR/Cas9 genome editing technology was used to generate a 1,233 bp deletion including exon 3, which encodes a large part of the tubulin-binding stathmin-like domain of the encoded protein and parts of the surrounding introns, as confirmed by DNA sequencing. Western blot analysis demonstrated absence of protein expression in brain lysates from adult homozygous mutant mice. (J:337175)