The targeting construct inserted into the 3'UTR an FRT-flanked stop cassette and loxP-Stop-loxP-IRES2-tTA-Advanced. Flp-mediated recombination removed the FRT-flanked stop cassette. Cre-mediated recombination removed the floxed stop cassette. (J:104881)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count