The targeting construct inserted the floxed arginine-glutamic acid dipeptide repeats inserted into intron 1. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the repeats. (J:104881)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count