A viral 2A oligopeptide, a iCre recombinase/ERT2 fusion followed by an FRT-flanked neomycin resistance cassette were inserted between the coding region of exon 2 and the 3' untranslated region in frame to the Bmp10 gene on chromosome 6 via homologous recombination in the ES cells. The expression of Bmp10 is not affected by the insertion. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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