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The Flpo recombinase gene and FRT flanked CAG-Hyg selection cassette were inserted at the first ATG site of the Cyp3a11 gene by targeted transgenesis with homologous recombination such that it is under the control of the Cyp3a11 promoter. The embryonic stem cells (ES) used were established from NOG mice and a clone a5363 bearing Portm1.1Jic was used. (J:336704)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
