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A CAG-Loxp-PGK-Neo-poly(A)-Loxp-Runx1 cassette was inserted into the Rosa26 locus. The cDNA containing a complete open reading frame of Runx1 was inserted after the second Loxp site. Constitutive Runx1 expression is observed upon removal of the STOP cassette by Cre-mediated recombination. (J:242690)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
