An IRES-cre sequence was inserted into the 3 UTR of the Cd40lg gene by homologous recombination. After obtaining germline transmission of the targeted allele, the FRT-flanked selection cassette was removed by crossing to Flpe transgenic mice. (J:327502)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count