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A cre recombinase gene and FRT-flanked neomycin resistance cassette were inserted at the translation initiation site in exon 2. Flp-mediated recombination removed the selection cassette as Col10a1tm2.1(cre)Ksec line described in J:122054. The recombination only took place in lower hypertrophic zone (HZ), which was delayed compared with that of Col10a1tm2.1(cre)Ksec line. (J:324690)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
