LoxP sites as well as an FRT-flanked neomycin resistance cassette were inserted to flank exons 5 and 6. The FRT-flanked neomycin resistance cassette was removed via FLP-mediated recombination in the germline. (J:288306)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count