LoxP sites were inserted approximately 1.6-kb upstream of the transcriptional start site and 300-bp downstream of the 3-UTR. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:294595)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count