Two loxP sites flanking a STOP cassette sequence and a frt-flanked PKG-neomycin cassette were inserted into intron 3. The frt-flanked PKG-neomycin cassette was removed via FLP-mediated recombination in the germline. (J:297217)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count