CRISPR/Cas9 genome editing technology was used to insert a termination codon near the start codon in the coding sequence. Western blotting and RT-PCR showed the absence of the encoded protein and transcript, respectively. (J:285409)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count