A loxP site was inserted upstream of the first exon and a self-deletion anchor (SDA)-flanked neomycin cassette and second loxP site were inserted downstream of exon 1.The neomycin cassette was self-excised leaving exon 1 floxed. (J:336197)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count