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The transgenic construct contains a human skeletal muscle alpha actin promoter and first exon (- 2,000 to + 239 relative to the transcription start site) promoter, a beta-globin intron II and a poly(A) tail followed by a modified reverse tetracycline-regulated transactivator (rtTA) from Tet3G. Mice from founder line 6 were found to have robust H2B-GFP expression in both slow- and fast-twitch muscles of the lower hind limbs. (J:336174)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
