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Exons 10 and 11 were flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted after the first loxP site, upstream of exon 10, and was removed via flp-mediated recombination. Exons 10-11 encode for the second substrate-binding site, the iron-binding site, part of the p450 domain, and the polyA signal. (J:274566)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
