The transgene consisting of the cDNA encoding Neh2 domain of the mouse Nrf2 gene (NRF2) fused to a Cre coding sequence followed by a CL1-PEST degradation signal was linked to the IRES-EGFP fragment and inserted downstream of the Mafg-regulatory domain (MGRD). Four founder progenies were obtained, and one of the transgenic mouse lines (line# 737) was selected and used for the studies. (J:331370)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA)F1
--
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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