Log In|Sign Up
EN
Aspartic acid codon 18 (GAC) was changed to asparagine (AAT) (p.D18N) using an sgRNA (targeting CCACTGGCCTGCCTTCGTCT) and an ssODN template with CRISPR/Cas9 technology. The equivalent human mutation is associated with familial chilblain lupus (FCL). (J:295560)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
