Exon 2 was flanked by loxP sites and an FRT-flanked neomycin resistance gene was inserted in intron 1 and an F3-flanked puromycin resistance gene in intron 2. The neomycin and puromycin genes were removed via flp-mediated recombination. (J:281424)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count