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The mouse NC14A domain (exons 17-18) was replaced with the human NC16A counterpart encoded by exons 18 and 19, which were flanked by loxP sites. A FRT-flanked neo cassette was removed via flp-mediated recombination. Cre-mediated recombination removed exons 18 and 19, maintaining the reading frame and resulting in an NC16A domain-truncated protein. (J:263966)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
