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The single exon and the 3 untranslated region containing the polyadenylation signal were flanked by loxP sites. A modified yellow fluorescent protein, YPet, cDNA was inserted downstream of the 3 loxP site such that when the floxed region is removed, YPet is expressed under the endogenous Htr1a promoter. An inserted FRT-flanked PGK-EM7-Neomycin minigene was removed via flp-mediated recombination. (J:254164)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
