A loxP site was inserted upstream of exon 3 and a second loxP site, FRT-flanked neomycin resistance cassette, and third loxp site in opposite orientation were inserted downstream of exon 3. Flp-mediated recombination removed the neomycin resistance cassette leaving exon 3 floxed. (J:246331)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count