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The 131.5 kb transgene consists of an RFP-IRES-CreERT2polyA expression cassette inserted into a mouse bacterial artificial chromosome (BAC) clone RP23-193N23 including Fgf1 5' UTR (127.7 kb), exon 1A, and 1B sequence containing the promoter for alternatively spliced to the first protein-coding exon 1A isoform predominantly expressed in the heart. Three founders 13A, 22A, and 25A were confirmed. Line #13A with the highest expression of Cre recombinase in the heart was chosen for all the following studies. (J:323281)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
