CRISPR/Cas9 technology using sgRNAs TATACGTAGGGTTGTGCCTCTGG and ATCGAGTCCCGTCAATTACACGG deleted exons 4 and 5. Western blot analysis confirmed absence of protein in the hippocampus. (J:333965)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count