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The open reading frame of the mouse Islr (Meflin) gene was inserted into the multiple cloning site of a tetracycline-inducible expression vector pTRE3G followed by microinjection into fertilized eggs of C57BL/6 mice. Of four lines with germline transmission generated, one line was established based on the confirmed doxycycline-mediated induction. (J:322997)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
