Log In|Sign Up
EN
This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AATTCTGGTCAGGGTACTCA targeting the 5' side and CTATAGGCTGGCCCATTGTC targeting the 3' side of a critical region (ENSMUSE0000105763 and ENSMUSE00001085011). This resulted in a 3841bp deletion of Chr5 from 87566792 to 87570632 with the insertion of aaaaaagaaagaaaaagaa (GRCm39), introducing a frameshift and premature stop codon. (J:265051)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
