CRISPR/Cas9 technology using gRNA 5-CACCACAAACACCGATGACTTGG-3 targeting exon 3 (the first coding exon) of both Myh1 and Myh4 genes generated a single nucleotide insertion in Myh4. This targeting event also generated a single nucleotide deletion in Myh1 (Myh1em1Ktsu) in this line. (J:335578)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count