The targeting construct inserted an IRES sequence followed by the mER:Cre:mER cDNA encoding a fusion protein with two copies of the mouse estrogen receptor (mER) flanking Cre recombinase, and a Neomycin resistance (NeoR) selection cassette flanked by Frt recombination sites in the Tbx3 gene. (J:232111)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count