The targeting construct inserted into intron 2 an inverted splice acceptor-membrane bound GFP cassette flanked by two pairs of loxP and lox2272 sites in opposite orientation. A loxP site was inserted upstream of exon 2. Dre-mediated recombination removed the Rox flanked neomycin resistance cassette. (J:319356)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count