CRISPR/Cas9 technology flanked exons 2-11 with loxP sites and inserted a P2A and EGFP between exon 11 and the second loxP site. Missense mutations were identified that result in the quenching of the GFP signal but do not influence IL-3Ralpha functionality or signaling. (J:335093)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count